Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 6/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386866 | 0.78 | CDK4 (0.44) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL19996585 | 0.76 | SLC6A4 (0.38) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL3177399 | 0.73 | CDK4 (0.42) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL15863347 | 0.73 | PLAU (0.41) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL645711 | 0.73 | CDK4 (0.45) | CDK4CCND1HTR2AHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL15863366 | 0.72 | PLAU (0.40) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL24999184 | 0.71 | CDK4 (0.42) | CDK4CCND1HTR2AHTR2CNOTUM | |
| SCHEMBL24218236 | 0.70 | CDK4 (0.42) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL1724156 | 0.69 | CDK4 (0.42) | CDK4CCND1HTR2AHTR2CHTR6 | |
| SCHEMBL15862652 | 0.66 | ALDH1A1 (0.44) | NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926293-B2 | Multivalent RAS binding compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-03-27 | — | — | US | disclosed |