Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349145 | 0.83 | CYP1A2 (0.47) | CYP1A2TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12259048 | 0.79 | — | — | |
| SCHEMBL12763781 | 0.71 | CYP1A2 (0.61) | CYP1A2TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13574526 | 0.69 | FDPS (0.47) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL4695990 | 0.69 | FDPS (0.47) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL20250826 | 0.67 | POLB (0.46) | TSHRALDH1A1SMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL11181812 | 0.66 | FFAR2 (0.49) | CYP1A2TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5096038 | 0.66 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12571300 | 0.65 | TSHR (0.59) | CYP1A2TSHRALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL10990156 | 0.65 | MAPK8 (0.41) | TSHRALDH1A1SMN1; SMN2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926282-B2 | Phthalazinones and isoquinolinones as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-27 | — | — | US | disclosed |