Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10042194 | 0.82 | HTT (0.58) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL309036 | 0.82 | IRAK4 (0.58) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL21567969 | 0.81 | HSD17B10 (0.71) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL16718858 | 0.81 | HSD17B10 (0.67) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| Hydrochloric Acid SCHEMBL31474423 | 0.80 | IRAK4 (0.57) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| Hydrochloric Acid SCHEMBL30152392 | 0.80 | IRAK4 (0.57) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL20250777 | 0.80 | HSD17B10 (0.53) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL309358 | 0.79 | HSD11B1 (0.57) | HSD17B10ALDH1A1LMNAHPGDIRAK4 | |
| SCHEMBL946897 | 0.79 | IRAK4 (0.68) | ALDH1A1IRAK4HTTKDM4ESMN1; SMN2 | |
| SCHEMBL21760511 | 0.79 | HSD17B10 (0.68) | HSD17B10ALDH1A1LMNAHPGDIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| US-9926282-B2 | Phthalazinones and isoquinolinones as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-27 | — | — | US | disclosed |