Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19030768 | 0.84 | LMNA (0.72) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL22857984 | 0.82 | ALDH1A1 (0.50) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL21331457 | 0.81 | ALDH1A1 (0.49) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL19997258 | 0.81 | HSD17B10 (0.57) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL31218890 | 0.81 | LMNA (0.54) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL22857935 | 0.81 | ALDH1A1 (0.49) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL29749543 | 0.80 | LMNA (0.54) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL17781106 | 0.79 | TGFBR1 (0.62) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL22857936 | 0.79 | HPGD (0.47) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL10042194 | 0.79 | HTT (0.58) | HSD17B10ALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954831-A | Pyrimidopyrazoles, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119894895-A | IRAK4 degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-116829562-B | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳国顺康医药科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119604512-A | TYK2 inhibitor and application thereof | 阿鲁米斯股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-115873000-B | Isoquinolinones and quinazolinones compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113527298-B | Macrocyclic lactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-113354653-B | Diaryl macrocyclic polymorphs and processes for their preparation | 特普医药公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113773335-B | Compound serving as protein kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118973581-A | IRAK degradation agent and application thereof | 凯麦拉医疗公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-110317214-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-110317213-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115052660-A | Substituted 7- (methylamino) pyrazolo [1,5-a ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052627-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115038705-A | 7- (methylamino) pyrazolo [1,5-a ] pyrimidine-3-carboxamide compounds | 伊莱利利公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022171139-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 北京国鸿生物医药科技有限公司 | 2022-08-18 | — | — | WO | disclosed |
| CN-110577532-B | Tropomyosin receptor kinase inhibitor and preparation method and application thereof | 江苏威凯尔医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110950889-B | Multi-target kinase inhibitor and preparation method and application thereof | 北京赛林泰医药技术有限公司 | 2022-04-05 | — | — | CN | disclosed |
| WO-2015073267-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2015073267-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-05-21 | — | — | WO | disclosed |