Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 5/20 | 0.34 |
| ▸ | GRB2 | P62993 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085619 | 1.00 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL19085728 | 1.00 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL17308684 | 0.86 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL17293237 | 0.86 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL17308624 | 0.86 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL17308685 | 0.83 | SLC7A5 (0.47) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL17292902 | 0.81 | PAK1 (0.44) | SLC7A5CYP3A4GRIK1GRIK2 | |
| SCHEMBL17308623 | 0.79 | SLC7A5 (0.42) | SLC7A5CYP3A4ALPIPKMPTGS1 | |
| SCHEMBL19085586 | 0.78 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 | |
| SCHEMBL5795469 | 0.76 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |