Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17308685 | 0.92 | SLC7A5 (0.47) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17308693 | 0.81 | SLC7A5 (0.37) | SLC7A5CYP3A4ALPIPKMPTGS1 | |
| SCHEMBL17293237 | 0.81 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17308624 | 0.81 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17308684 | 0.81 | SLC7A5 (0.43) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL19085728 | 0.78 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL19085619 | 0.78 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL19997403 | 0.78 | SLC7A5 (0.41) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17308667 | 0.76 | SLC6A5 (0.44) | — | |
| SCHEMBL17292902 | 0.75 | PAK1 (0.44) | SLC7A5CYP3A4GRIK1CYP1A2GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | TETRAHEDRON (FR) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | AHCYL1, CBS, H1-5 | SLC7A5 79/4885CYP3A4 2019/4885GRIA2 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.