Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849695 | 0.76 | MEN1 (0.55) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL22364147 | 0.76 | QPCT (0.37) | MEN1KMT2AALDH1A1QPCTMAPKAPK2 | |
| SCHEMBL6209344 | 0.72 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6208095 | 0.72 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11504339 | 0.70 | ALDH1A1 (0.60) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL2833590 | 0.70 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14489950 | 0.69 | MEN1 (0.57) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1276388 | 0.68 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11311904 | 0.67 | KMT2A (0.55) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10907938 | 0.67 | KMT2A (0.55) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10753942-B2 | Methods to detect remnant cancer cells | INDICATOR SYSTEMS INTERNATIONAL, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190107543-A1 | METHODS TO DETECT REMNANT CANCER CELLS | INDICATOR SYSTEMS INTERNATIONAL, INC. (US) | 2019-04-11 | — | — | US | disclosed |
| US-10239891-B2 | Compositions to detect remnant cancer cells | INDICATOR SYSTEMS INTERNATIONAL, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-9926334-B1 | — | — | 2018-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239891-B2 | Compositions to detect remnant cancer cells | MKI67, TP53, RNASE1 | MEN1 1389/4885KMT2A 3104/4885RAB9A 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.