Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 19/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997614 | 0.92 | WDR5 (0.75) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19991530 | 0.91 | WDR5 (0.80) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19997596 | 0.89 | WDR5 (1.00) | WDR5ALDH1A1 | |
| SCHEMBL19997602 | 0.89 | WDR5 (1.00) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19998129 | 0.88 | WDR5 (0.81) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19997654 | 0.87 | WDR5 (0.74) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19997622 | 0.85 | WDR5 (0.66) | WDR5 | |
| SCHEMBL19997671 | 0.85 | WDR5 (0.71) | WDR5ALDH1A1 | |
| SCHEMBL19997606 | 0.85 | WDR5 (0.71) | WDR5ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19997607 | 0.84 | WDR5 (1.00) | WDR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086767-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086767-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR77 | WDR5 1/4885ALDH1A1 3489/4885KDM4E 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.