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Sugi Predict / Targets / WDR77

WDR77

Methylosome protein WDR77 · Q9BQA1 · WDR77 on Sugi Atlas →

88,084 patent compounds predicted against WDR77, 46,301 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL733579 SCHEMBL733579 0.56 19/20
SCHEMBL474871 SCHEMBL474871 0.78 18/20
SCHEMBL733472 SCHEMBL733472 0.78 18/20
SCHEMBL733339 SCHEMBL733339 0.53 17/20
SCHEMBL730671 SCHEMBL730671 0.51 17/20
SCHEMBL731192 SCHEMBL731192 0.51 17/20
SCHEMBL873740 SCHEMBL873740 0.51 17/20
SCHEMBL496381 SCHEMBL496381 0.56 14/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL495605) 0.55 14/20
SCHEMBL474831 SCHEMBL474831 0.54 14/20
SCHEMBL731888 SCHEMBL731888 0.54 14/20
SCHEMBL733393 SCHEMBL733393 0.52 14/20
SCHEMBL474927 SCHEMBL474927 0.49 13/20
Beta-2'-C-Methyl-7-Deaza-Adenosine Beta-2'-C-Methyl-7-Deaza-Adenosine (SCHEMBL731022) 0.57 12/20
Beta-2'-C-Methyl-7-Deaza-Adenosine Beta-2'-C-Methyl-7-Deaza-Adenosine (SCHEMBL733423) 0.57 12/20
SCHEMBL731889 SCHEMBL731889 0.52 12/20
SCHEMBL496566 SCHEMBL496566 0.45 12/20
SCHEMBL496318 SCHEMBL496318 0.50 10/20
SCHEMBL496319 SCHEMBL496319 0.50 10/20
SCHEMBL475133 SCHEMBL475133 0.49 10/20

Clinical trials — most relevant to WDR77 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study PHASE3COMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration nanUNKNOWN
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Microarray Analysis in Syndromic Obesity nanCOMPLETED
Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity. nanRECRUITING
Identification of the Genetic Causes of Rare Diseases With Negative Exome Findings nanUNKNOWN
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing nanRECRUITING
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study nanCOMPLETED
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
Finding Genes With NGS Techniques in Whom Mutations Cause Neurological Diseases nanUNKNOWN
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature. nanUNKNOWN
A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy nanCOMPLETED
Chromosome 18 Clinical Research Center nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Gene x Behavior Interaction in the Look AHEAD Study nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Inherited Reproductive Disorders nanRECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Natural History and Genetic Studies of Usher Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a WDR77 binder may also engage these)

ProteinNameSimilarity
Q4QR85 — 1.000 Q4QR85 →
Q5RBZ2 — 1.000 Q5RBZ2 →
Q5E9I7 — 1.000 Q5E9I7 →
Q99J09 — 1.000 Q99J09 →
Q6P4I2 — 0.984 Q6P4I2 →
Q9CWR1 — 0.979 Q9CWR1 →
Q6NUD0 — 0.976 Q6NUD0 →
Q9JHB4 — 0.975 Q9JHB4 →
Q9DB94 — 0.972 Q9DB94 →
A0A1L8HX76 — 0.971 A0A1L8HX76 →
Q86W42 — 0.971 Q86W42 →
Q6AY87 — 0.970 Q6AY87 →
A5D8Q8 — 0.969 A5D8Q8 →
Q96KV7 — 0.969 Q96KV7 →
Q9HCU5 — 0.969 Q9HCU5 →
E9Q349 — 0.969 E9Q349 →
Q9BTV6 — 0.969 Q9BTV6 →
Q8C5V5 — 0.968 Q8C5V5 →
Q567G2 — 0.967 Q567G2 →
Q5U4D9 — 0.967 Q5U4D9 →
A7E3S5 — 0.966 A7E3S5 →
Q8NA23 — 0.966 Q8NA23 →
Q9NNW5 — 0.965 Q9NNW5 →
Q9WTV0 — 0.965 Q9WTV0 →
P57081 — 0.965 P57081 →
Q8CFD5 — 0.964 Q8CFD5 →
A7Z052 — 0.964 A7Z052 →
Q32KQ2 — 0.964 Q32KQ2 →
Q5U4F6 — 0.964 Q5U4F6 →
Q6KAU8 — 0.964 Q6KAU8 →