Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | PRKACA | P17612 | 3/20 | 0.37 |
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PRKX | P51817 | 2/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.37 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12263568 | 0.74 | AOC3 (0.53) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| SCHEMBL2865073 | 0.71 | CLK4 (0.38) | CLK4CYP3A4MAPK1CYP2D6CYP2C9 | |
| SCHEMBL8285034 | 0.71 | AOC3 (0.47) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| Hydrochloric Acid SCHEMBL4928857 | 0.70 | AOC3 (0.46) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| Hydrochloric Acid SCHEMBL30438393 | 0.70 | AOC3 (0.46) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| SCHEMBL10781087 | 0.69 | AOC3 (0.54) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| SCHEMBL10781776 | 0.69 | AOC3 (0.54) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| SCHEMBL3621393 | 0.68 | AOC3 (0.46) | AOC3L3MBTL1CASRCYP3A4MAPK1 | |
| SCHEMBL335622 | 0.67 | TAAR1 (0.56) | AOC3L3MBTL1CASRCYP3A4TAAR1 | |
| SCHEMBL135107 | 0.67 | TAAR1 (0.56) | AOC3L3MBTL1CASRCYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885486-B1 | AFFINITY ADSORBENTS FOR FACTOR VIII AND VON WILLEBRAND'S FACTOR | PROMETIC BIOSCIENCES LTD (GB) | 2016-03-23 | — | — | EP | disclosed |
| US-7960182-B2 | Affinity adsorbents for Factor VIII and von Willebrand's Factor | PROMETIC BIOSCIENCES LTD. (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20090275141-A1 | Affinity Adsorbents for Factor VIII and Von Willebrand's Factor | DEPARTMENT OF ECONOMIC DEVELOPMENT (IM) | 2009-11-05 | — | — | US | disclosed |
| EP-1885486-A1 | AFFINITY ADSORBENTS FOR FACTOR VIII AND VON WILLEBRAND'S FACTOR | Prometic Biosciences Ltd (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006120427-A1 | AFFINITY ADSORBENTS FOR FACTOR VIII AND VON WILLEBRAND'S FACTOR | PROMETIC BIOSCIENCES LTD. (GB) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275141-A1 | Affinity Adsorbents for Factor VIII and Von Willebrand's Factor | F8, F13B, F12 | AOC3 130/4885L3MBTL1 3465/4885CASR 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.