SCHEMBL2865073

SCHEMBL2865073

COc1cccc(C(Cl)(Cl)Cl)c1.ClC(Cl)(Cl)c1ncncn1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 3/20 0.38
DYRK1A Q13627 1/20 0.38
ACHE P22303 1/20 0.37
KIF11 P52732 1/20 0.37
EGFR P00533 3/20 0.36
MAPT P10636 5/20 0.36
NPC1 O15118 2/20 0.36
ERBB3 P21860 1/20 0.36
CYP3A4 P08684 6/20 0.36
ALDH1A1 P00352 4/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CYP1A2 P05177 5/20 0.36
CYP2D6 P10635 5/20 0.36
CYP2C19 P33261 5/20 0.36
MAPK1 P28482 4/20 0.36
HSD17B10 Q99714 3/20 0.36
MEN1 O00255 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10644920 0.83 ACHE (0.50) CLK4DYRK1AACHEKIF11NPC1
SCHEMBL5447490 0.80 ACHE (0.35) ACHEKIF11CYP3A4ALDH1A1CYP1A2
SCHEMBL2464063 0.78 CYP19A1 (0.42) KIF11CYP3A4ALDH1A1CYP1A2CYP2C19
SCHEMBL3265568 0.76 TSHR (0.39) KIF11EGFRALDH1A1MAPK1KDM4E
SCHEMBL607283 0.75 TSHR (0.58) ACHEEGFRMAPTCYP3A4ALDH1A1
SCHEMBL3208807 0.73 PTPN1 (0.37) EGFRCYP3A4ALDH1A1CYP1A2CYP2D6
Mequinol SCHEMBL8857366 0.73 LTA4H (0.48) MAPTNPC1ALDH1A1MAPK1MEN1
SCHEMBL2454679 0.73 GRM5 (0.40) CLK4KIF11CYP3A4CYP1A2CYP2D6
SCHEMBL4480152 0.73 ACHE (0.50) CLK4DYRK1AACHEKIF11NPC1
SCHEMBL1999873 0.71 AOC3 (0.39) CLK4DYRK1ACYP3A4ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11479620-B2 3D printing with polymeric nanogel particles THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-10-25 US claimed
US-20200283548-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2020-09-10 US claimed
EP-3685231-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES The Regents Of The University Of Colorado, A Body Corporate, A Colorado Non-Profit (US) 2020-07-29 EP claimed
WO-2019056019-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-03-21 WO claimed
WO-2023077159-A1 LOW VISCOSITY URETHANE (METH)ACRYLATE MONOMERS AND THEIR USE IN PRODUCTION OF TOUGH POLYMERS WITH WELL-CONTROLLED MODULUS AND STRENGTH THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-05-04 WO disclosed
WO-2022087464-A1 POLYMERIZABLE COMPOSITION FOR DENTAL TOOTH AND MATERIAL 3D PRINTING HYBRID CERAMIC (US) 2022-04-28 WO disclosed
US-10968300-B2 Control of polymer network structures via nanogels THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-04-06 US disclosed
US-20200283548-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2020-09-10 US disclosed
US-20200247927-A1 CONTROL OF POLYMER NETWORK STRUCTURES VIA NANOGELS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-08-06 US disclosed
EP-3685231-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES The Regents Of The University Of Colorado, A Body Corporate, A Colorado Non-Profit (US) 2020-07-29 EP disclosed
EP-3475323-A1 CONTROL OF POLYMER NETWORK STRUCTURES VIA NANOGELS The Regents of the University of Colorado, a body corporate (US) 2019-05-01 EP disclosed
WO-2019056019-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-03-21 WO disclosed
EP-2828314-A1 WATER COMPATIBLE NANOGEL COMPOSITIONS The Regents of the University of Colorado (US) 2015-01-28 EP disclosed
WO-2013142354-A1 WATER COMPATIBLE NANOGEL COMPOSITIONS THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2013-09-26 WO disclosed
US-8404402-B2 Photopolymerisable system for hologram formation SONY DADC AUSTRIA AG (AT) 2013-03-26 US disclosed
US-20100248088-A1 PHOTOPOLYMERISABLE SYSTEM FOR HOLOGRAM FORMATION SONY DADC AUSTRIA AG (AT) 2010-09-30 US disclosed
EP-2233976-A1 Photopolymerisable system for hologram formation Sony DADC Austria AG (AT) 2010-09-29 EP disclosed
EP-1663645-A1 METHOD TO REMOVE UNWANTED, UNEXPOSED, RADIATION-SENSITIVE LAYER IN A LITHOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics, LLC (US) 2006-06-07 EP disclosed
WO-2005025867-A1 METHOD TO REMOVE UNWANTED, UNEXPOSED, RADIATION-SENSITIVE LAYER IN A LITHOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS, LLC (US) 2005-03-24 WO disclosed
US-6843176-B2 Method to remove unwanted, unexposed, radiation-sensitive layer in a lithographic printing plate KODAK POLYCHROME GRAPHICS, LLC (US) 2005-01-18 US disclosed