Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CPT1A | P50416 | 10/20 | 0.51 |
| ▸ | CPT1B | Q92523 | 8/20 | 0.51 |
| ▸ | CPT2 | P23786 | 6/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997840 | 0.90 | CYP2C9 (0.56) | CYP2C9CPT1ACPT1BCPT2 | |
| SCHEMBL4055322 | 0.90 | CYP2C9 (0.56) | CYP2C9CPT1ACPT1BCPT2NR1H3 | |
| SCHEMBL2001755 | 0.84 | RORC (0.55) | CYP2C9CPT1ARORCNR1H2NR1H3 | |
| SCHEMBL2001874 | 0.81 | CNR1 (0.66) | CPT1ACPT1BCPT2RORCNR1H2 | |
| SCHEMBL2001650 | 0.80 | CNR1 (0.67) | CYP2C9CPT1ACPT1BCPT2RORC | |
| SCHEMBL28823982 | 0.79 | RORC (0.66) | CYP2C9CPT1ACPT1BCPT2RORC | |
| SCHEMBL5021967 | 0.78 | CPT1A (0.60) | CYP2C9CPT1ACPT1BCPT2RORC | |
| SCHEMBL5021974 | 0.77 | CPT1A (0.56) | CYP2C9CPT1ACPT1BCPT2RORC | |
| SCHEMBL5021972 | 0.76 | CPT1A (0.58) | CYP2C9CPT1ACPT1BCPT2RORC | |
| SCHEMBL25442267 | 0.75 | NR1H3 (0.50) | CYP2C9CPT1ACPT1BCPT2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960376-B2 | Benzo-fused heterocycles | CARA THERAPEUTICS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20090075973-A1 | BENZO-FUSED HETEROCYCLES | CARA THERAPEUTICS, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| WO-2009035997-A2 | BENZO-FUSED HETEROCYCLES | CARA THERAPEUTICS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075973-A1 | BENZO-FUSED HETEROCYCLES | CNR1, CNR2, TRPV1 | CYP2C9 210/4885CPT1A 1957/4885CPT1B 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.