Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.55 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 9/20 | 0.52 |
| ▸ | PPARA | Q07869 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956153 | 0.85 | GSTP1 (0.56) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL7977007 | 0.85 | GSTP1 (0.56) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL12569093 | 0.82 | PDE7A (0.46) | ALDH1A1MAPTKDM4EHPGDPDE7A | |
| SCHEMBL20280002 | 0.82 | GSTP1 (0.49) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL27129942 | 0.82 | GSTP1 (0.49) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL29500880 | 0.82 | PPARG (0.47) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL28991675 | 0.81 | GSTP1 (0.52) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL28991676 | 0.81 | GSTP1 (0.52) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL30317995 | 0.81 | GSTP1 (0.52) | GSTP1GSTM2PPARGPPARAALDH1A1 | |
| SCHEMBL1999221 | 0.81 | PPARA (0.55) | GSTP1GSTM2PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960373-B2 | 2-alkoxy-3,4,5-trihydroxyalkylamide-benzothiazepines preparation thereof, compositions containing them and use thereof | SANOFI-AVENTIS (FR) | 2011-06-14 | — | — | US | disclosed |
| US-20090093459-A1 | 2-ALKOXY-3,4,5-TRIHYDROXYALKYLAMIDE-BENZOTHIAZEPINES PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093459-A1 | 2-ALKOXY-3,4,5-TRIHYDROXYALKYLAMIDE-BENZOTHIAZEPINES PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | TPH2, CYP4B1, HTR3C | GSTP1 1330/4885GSTM2 1655/4885PPARG 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.