SCHEMBL20000063

SCHEMBL20000063

Cc1c(N)c(C)c(S(=O)(=O)NCC(F)(F)F)c(C)c1N

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA12 O43570 3/20 0.42
CA9 Q16790 3/20 0.42
ALDH1A1 P00352 1/20 0.34
PIK3CD O00329 4/20 0.33
PIK3CG P48736 4/20 0.33
PIK3CB P42338 3/20 0.33
PIK3C3 Q8NEB9 1/20 0.33
ILK Q13418 1/20 0.33
FABP4 P15090 1/20 0.33
PIK3CA P42336 1/20 0.32
CYP19A1 P11511 1/20 0.32
PNMT P11086 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000066 0.83 CA12 (0.36) CA1CA2CA12CA9PIK3CD
SCHEMBL20000091 0.83 CA2 (0.39) CA1CA2CA12CA9ALDH1A1
SCHEMBL20000090 0.81 CA12 (0.37) CA1CA2CA12CA9PIK3CD
SCHEMBL13810902 0.71 CA1 (0.52) CA1CA2FABP4
SCHEMBL20000064 0.70 SMN1; SMN2 (0.37) CA1CA2CA12CA9ALDH1A1
SCHEMBL20000069 0.69 CA12 (0.33) CA1CA2CA12CA9
SCHEMBL20000067 0.67 CA12 (0.34) CA1CA2CA12CA9
SCHEMBL22589610 0.67 CA9 (0.47) CA1CA2CA12CA9CA7
SCHEMBL29365989 0.67 CA9 (0.47) CA1CA2CA12CA9CA7
SCHEMBL21135362 0.66 PLA2G1B (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-20190076777-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-14 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed