SCHEMBL20000090

SCHEMBL20000090

CCc1c(N)c(C)c(S(=O)(=O)NCC(F)(F)F)c(CC)c1N

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
PIK3CD O00329 2/20 0.31
PIK3CB P42338 2/20 0.31
PIK3CG P48736 2/20 0.31
PIK3CA P42336 1/20 0.31
PIK3C3 Q8NEB9 1/20 0.30
ILK Q13418 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000066 0.91 CA12 (0.36) CA12CA1CA2CA9PIK3CD
SCHEMBL20000067 0.86 CA12 (0.34) CA12CA1CA2CA9
SCHEMBL20000063 0.81 CA1 (0.42) CA12CA1CA2CA9PIK3CD
SCHEMBL20000061 0.78
SCHEMBL20000069 0.77 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL20000065 0.72 KDM4E (0.36) CA12CA1CA2CA9
SCHEMBL20000089 0.68 ALDH1A1 (0.32)
SCHEMBL20000076 0.67 GAA (0.31)
SCHEMBL20000091 0.67 CA2 (0.39) CA12CA1CA2CA9
SCHEMBL13810902 0.65 CA1 (0.52) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-20190076777-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-14 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed