SCHEMBL20000077

SCHEMBL20000077

CCc1c(N)c(C)c(N)c(C)c1S(=O)(=O)NC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
HSD11B1 P28845 1/20 0.33
CA1 P00915 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
PNMT P11086 1/20 0.32
KMT2A Q03164 3/20 0.32
EPHX2 P34913 1/20 0.31
DHFR P00374 1/20 0.31
GFER P55789 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809930 0.95 LMNA (0.40) LMNAALDH1A1CA12CA2CA7
SCHEMBL20000079 0.92 LMNA (0.39) LMNAALDH1A1CA12CA2CA7
SCHEMBL20000062 0.87 ALDH1A1 (0.45) LMNAALDH1A1CA12CA2CA7
SCHEMBL20000061 0.67
SCHEMBL20000076 0.67 GAA (0.31) SMN1; SMN2
SCHEMBL31143645 0.66 LMNA (0.58) LMNAALDH1A1CA12CA2CA7
SCHEMBL20000078 0.64 ALDH1A1 (0.34) ALDH1A1CA12CA2CA7MAPT
SCHEMBL19798451 0.64 CA12 (0.46) LMNAALDH1A1CA12CA2CA7
SCHEMBL31143732 0.63 ALDH1A1 (0.51) LMNAALDH1A1MAPTHSD11B1KMT2A
SCHEMBL4066656 0.63 LMNA (0.51) LMNAALDH1A1CA12CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed