Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 9/20 | 0.67 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988712 | 1.00 | FPR1 (0.67) | FPR1KDM1AFPR2PDE4BMAOB | |
| SCHEMBL19972286 | 0.88 | FPR1 (0.71) | FPR1FPR2POLBTDP1 | |
| SCHEMBL19988405 | 0.83 | FPR1 (0.67) | FPR1FPR2PDE4BSCN9A | |
| SCHEMBL19988380 | 0.83 | FPR1 (0.63) | FPR1KDM1AFPR2PDE4BMAOB | |
| SCHEMBL20001277 | 0.83 | FPR1 (0.63) | FPR1KDM1AFPR2PDE4BMAOB | |
| SCHEMBL19988708 | 0.80 | FPR1 (1.00) | FPR1FPR2 | |
| SCHEMBL19972268 | 0.80 | FPR1 (1.00) | FPR1FPR2 | |
| SCHEMBL19972270 | 0.80 | FPR1 (1.00) | FPR1FPR2 | |
| SCHEMBL21342018 | 0.78 | KDM1A (0.47) | FPR1KDM1AFPR2PDE4BMAOB | |
| SCHEMBL21342410 | 0.78 | KDM1A (0.47) | FPR1KDM1AFPR2PDE4BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |