Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 6/20 | 0.47 |
| ▸ | FPR2 | P25090 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342410 | 1.00 | KDM1A (0.47) | KDM1AFPR1FPR2MMP2MMP1 | |
| SCHEMBL21332026 | 0.88 | FPR1 (0.49) | FPR1FPR2MMP2MMP1MMP3 | |
| SCHEMBL21342456 | 0.85 | FPR1 (0.53) | KDM1AFPR1FPR2PDE4BMAOA | |
| SCHEMBL21342020 | 0.85 | FPR1 (0.60) | KDM1AFPR1FPR2MMP2MMP1 | |
| SCHEMBL21341988 | 0.83 | FPR1 (0.48) | FPR1FPR2MMP2MMP1MMP3 | |
| SCHEMBL21342015 | 0.83 | KDM1A (0.44) | KDM1AFPR1FPR2CYP3A4CYP2C19 | |
| SCHEMBL21342340 | 0.81 | LMNA (0.51) | KDM1APDE4B | |
| SCHEMBL21342429 | 0.81 | SMN1; SMN2 (0.51) | KDM1AFPR1FPR2PDE4B | |
| SCHEMBL21342327 | 0.80 | FPR1 (0.73) | FPR1FPR2 | |
| SCHEMBL21342328 | 0.80 | FPR1 (0.73) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |