Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20001266 | 0.90 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3319370 | 0.88 | TSHR (0.75) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9162964 | 0.86 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17489178 | 0.85 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL457682 | 0.84 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18101451 | 0.84 | TSHR (0.67) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.84 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2156739 | 0.83 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL20029770 | 0.83 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11600594 | 0.82 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110198-B2 | Polymer particles | TERUMO CORPORATION (JP) | 2021-09-07 | — | — | US | disclosed |
| US-20200215222-A1 | POLYMER PARTICLES | MICROVENTION, INC. | 2020-07-09 | — | — | US | disclosed |
| US-10328175-B2 | Polymer particles | TERUMO CORPORATION (JP) | 2019-06-25 | — | — | US | disclosed |
| US-20180085487-A1 | POLYMER PARTICLES | TERUMO CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200215222-A1 | POLYMER PARTICLES | FGB, PLG, PLAT | TSHR 2814/4885THRB 4520/4885POLB 379/4885 |
| US-10328175-B2 | Polymer particles | PCBP1, LCP1, PSAP | TSHR 4408/4885THRB 4856/4885POLB 121/4885 |
| US-20180085487-A1 | POLYMER PARTICLES | PCBP1, LCP1, PSAP | TSHR 4408/4885THRB 4856/4885POLB 121/4885 |
| US-11110198-B2 | Polymer particles | FGB, PLG, PLAT | TSHR 2814/4885THRB 4520/4885POLB 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.