Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893138 | 0.85 | GRM5 (0.63) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL3348910 | 0.82 | GRM5 (0.66) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL2893109 | 0.81 | GRM5 (0.58) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL2891556 | 0.81 | GRM5 (0.58) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL743098 | 0.81 | GRM5 (0.58) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL15991177 | 0.81 | GRM5 (0.58) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL14995149 | 0.80 | GRM5 (0.70) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL19989696 | 0.79 | GRM5 (0.69) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL941018 | 0.78 | GRM5 (0.61) | GRM5ESR2PDK4GRM1NAMPT | |
| SCHEMBL30437960 | 0.77 | GRM5 (0.54) | GRM5ESR2PDK4GRM1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018062924-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG-A ST CO., LTD. (KR) | 2018-04-05 | — | — | WO | disclosed |
| US-20180086709-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG-A ST CO., LTD. (KR) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086709-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | GALE, UGDH, PGLS | GRM5 1014/4885ESR2 4278/4885PDK4 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.