Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729320 | 0.79 | LMNA (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL16892234 | 0.79 | TSHR (0.34) | TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL16892243 | 0.79 | TSHR (0.34) | TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL21341350 | 0.77 | TSHR (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL4957529 | 0.77 | — | — | |
| SCHEMBL1965395 | 0.77 | — | — | |
| SCHEMBL16887513 | 0.76 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL24011102 | 0.74 | TP53 (0.56) | SMN1; SMN2 | |
| SCHEMBL16886397 | 0.74 | TSHR (0.32) | TSHRSMN1; SMN2 | |
| SCHEMBL16886396 | 0.74 | TSHR (0.32) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |