Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16886397 | 1.00 | TSHR (0.32) | TSHRSMN1; SMN2 | |
| SCHEMBL16704552 | 0.82 | POLB (0.37) | SMN1; SMN2 | |
| SCHEMBL6140852 | 0.82 | — | — | |
| SCHEMBL18768899 | 0.82 | POLB (0.37) | SMN1; SMN2 | |
| SCHEMBL18751737 | 0.82 | POLB (0.37) | SMN1; SMN2 | |
| SCHEMBL16886394 | 0.81 | — | — | |
| SCHEMBL16886395 | 0.81 | — | — | |
| SCHEMBL16892243 | 0.76 | TSHR (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL22729320 | 0.76 | LMNA (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL16892234 | 0.76 | TSHR (0.34) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458171-B2 | Pyrrolidinyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150191483-A1 | PYRROLIDINYL SULFONE RORGAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191483-A1 | PYRROLIDINYL SULFONE RORGAMMA MODULATORS | RORC, RORB, RORA | TSHR 538/4885SMN1; SMN2 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.