Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437592 | 0.79 | TP53 (0.50) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL4004484 | 0.77 | KMT2A (0.45) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL657937 | 0.77 | POLB (0.47) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL2366245 | 0.77 | POLB (0.44) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| Lithium Ion SCHEMBL29771299 | 0.76 | POLB (0.42) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| Hydrochloric Acid SCHEMBL30612668 | 0.76 | L3MBTL1 (0.46) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL9670998 | 0.74 | POLB (0.45) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL6918970 | 0.74 | L3MBTL1 (0.53) | KMT2AMEN1POLBL3MBTL1EPHX2 | |
| SCHEMBL815029 | 0.74 | TSHR (0.50) | ALDH1A1LMNA | |
| SCHEMBL15592626 | 0.73 | L3MBTL1 (0.44) | KMT2AMEN1POLBL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |