Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002083 | 0.79 | — | — | |
| SCHEMBL15114425 | 0.79 | — | — | |
| SCHEMBL16892209 | 0.77 | GRM2 (0.36) | APLNR | |
| SCHEMBL16892211 | 0.77 | GRM2 (0.36) | APLNR | |
| SCHEMBL20002088 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL20002225 | 0.76 | APLNR (0.38) | APLNR | |
| SCHEMBL20002730 | 0.76 | — | — | |
| SCHEMBL15116459 | 0.71 | — | — | |
| SCHEMBL18309 | 0.70 | APLNR (0.39) | APLNR | |
| SCHEMBL19633128 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |