Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002208 | 0.82 | PDK2 (0.30) | PDK2 | |
| SCHEMBL20002206 | 0.74 | CYP1A2 (0.32) | — | |
| SCHEMBL16015894 | 0.73 | CYP1A2 (0.34) | PDK2 | |
| SCHEMBL20002204 | 0.72 | CYP1A2 (0.35) | PDK2 | |
| SCHEMBL29173251 | 0.72 | LMNA (0.32) | PDK2 | |
| SCHEMBL16886245 | 0.71 | CYP1A2 (0.30) | — | |
| SCHEMBL2370073 | 0.70 | — | — | |
| SCHEMBL12290682 | 0.70 | CYP1A2 (0.37) | — | |
| SCHEMBL20002203 | 0.70 | — | — | |
| SCHEMBL16886242 | 0.69 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |