Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003202 | 0.82 | PDK2 (0.31) | PDK2 | |
| SCHEMBL20002818 | 0.77 | LIPA (0.32) | — | |
| SCHEMBL16886244 | 0.74 | LIPA (0.30) | — | |
| SCHEMBL16309031 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL16309032 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL24408666 | 0.67 | — | — | |
| SCHEMBL20002205 | 0.64 | LIPA (0.32) | — | |
| SCHEMBL685791 | 0.63 | LIPA (0.33) | — | |
| SCHEMBL732453 | 0.63 | SHBG (0.36) | — | |
| SCHEMBL11888192 | 0.63 | SHBG (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |