Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.75 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003388 | 1.00 | AR (0.78) | ARHDAC1PGR | |
| SCHEMBL20003475 | 1.00 | AR (0.78) | ARHDAC1PGR | |
| SCHEMBL20003386 | 0.99 | AR (0.80) | ARHDAC1PGR | |
| SCHEMBL20003340 | 0.96 | AR (0.81) | ARHDAC1 | |
| SCHEMBL8865594 | 0.92 | AR (0.78) | ARHDAC1PGR | |
| SCHEMBL8516863 | 0.92 | AR (0.79) | ARHDAC1 | |
| Hydrochloric Acid SCHEMBL22656831 | 0.91 | AR (0.77) | ARHDAC1 | |
| SCHEMBL3873665 | 0.90 | AR (0.75) | ARHDAC1PGR | |
| SCHEMBL3871464 | 0.90 | AR (0.75) | ARHDAC1PGR | |
| SCHEMBL8517259 | 0.90 | AR (0.80) | ARHDAC1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238145-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210069154-A1 | Treatment of Breast Cancer | MEDIVATION PROSTATE THERAPEUTICS LLC | 2021-03-11 | — | — | US | disclosed |
| US-20180086718-A1 | Diarylhydantoin Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086718-A1 | Diarylhydantoin Compounds | BPHL, AR, SHBG | AR 2/4885HDAC1 183/4885PGR 404/4885 |
| US-20210069154-A1 | Treatment of Breast Cancer | BRCA1, TP53, TUBB6 | AR 2403/4885HDAC1 2205/4885PGR 5/4885 |
| US-20210238145-A1 | DIARYLHYDANTOIN COMPOUNDS | BPHL, AR, SHBG | AR 2/4885HDAC1 183/4885PGR 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.