SCHEMBL20003531

SCHEMBL20003531

CC([SiH2]C1CCCCC1)C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
EPHX1 P07099 2/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
MMP2 P08253 2/20 0.31
CA9 Q16790 2/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15915938 0.76 SHBG (0.31) SHBG
SCHEMBL15914506 0.73
SCHEMBL9011820 0.72 SHBG (0.39) SHBGEPHX1CA12CA1CA2
SCHEMBL27752398 0.69
SCHEMBL236035 0.68 TDP1 (0.32)
SCHEMBL15915274 0.68 SHBG (0.41) SHBGEPHX1
SCHEMBL2995478 0.68 SHBG (0.50) SHBGEPHX1CA12CA1CA2
SCHEMBL5412 0.66 SHBG (0.48) SHBGEPHX1CA12CA1CA2
Cyclohexane SCHEMBL5321429 0.66 SHBG (0.48) SHBGEPHX1CA12CA1CA2
SCHEMBL21575869 0.66 SHBG (0.48) SHBGEPHX1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2792728-B1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DAINIPPON INK & CHEMICALS (JP) 2018-03-28 EP disclosed