SCHEMBL20003652

SCHEMBL20003652

BCc1ccc(-c2cc(F)c(C(F)(F)Oc3cc(F)c(F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33
ANPEP P15144 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17736129 0.86 KIF11 (0.33) KIF11ANPEP
SCHEMBL15965522 0.86 KIF11 (0.33) KIF11ANPEP
SCHEMBL14255360 0.84 ANPEP (0.34) KIF11ANPEP
SCHEMBL503178 0.84 RARB (0.35) KIF11
SCHEMBL17108380 0.84 RARB (0.35) KIF11
SCHEMBL15965527 0.82 RARB (0.41)
SCHEMBL21937826 0.82 RARB (0.41)
SCHEMBL17827769 0.82 F10 (0.34) KIF11ANPEP
SCHEMBL13671383 0.82 KIF11 (0.31) KIF11
SCHEMBL16982674 0.81 KIF11 (0.45) KIF11ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2792728-B1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DAINIPPON INK & CHEMICALS (JP) 2018-03-28 EP disclosed