SCHEMBL17827769

SCHEMBL17827769

Fc1cc(OC(F)(F)c2c(F)cc(-c3ccc(CC4CC4)cc3)cc2F)cc(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.34
GRM2 Q14416 9/20 0.33
RPS6KB1 P23443 2/20 0.32
KIF11 P52732 1/20 0.31
MGAT2 Q10469 1/20 0.31
ANPEP P15144 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16978492 0.95 LTA4H (0.33) F10GRM2RPS6KB1
SCHEMBL17827767 0.92 GRM2 (0.37) F10GRM2KIF11
SCHEMBL17827775 0.89 GPR84 (0.35) F10KIF11
SCHEMBL16978487 0.84 F10 (0.32) F10
SCHEMBL17827770 0.84 GRM2 (0.34) F10GRM2
SCHEMBL17070199 0.83 F10 (0.32) F10
SCHEMBL17655005 0.82 MOGAT2 (0.36) F10
SCHEMBL17736129 0.82 KIF11 (0.33) GRM2KIF11ANPEP
SCHEMBL20003652 0.82 KIF11 (0.33) KIF11ANPEP
SCHEMBL15965522 0.82 KIF11 (0.33) GRM2KIF11ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994769-B2 Liquid crystal composition SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2018-06-12 US disclosed
US-20170015906-A1 LIQUID CRYSTAL COMPOSITION SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2017-01-19 US disclosed
US-20170015906-A1 LIQUID CRYSTAL COMPOSITION SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2017-01-19 US disclosed
US-9404038-B2 Cyclopropyl-bearing liquid crystal compounds and mixtures SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-08-02 US disclosed
US-9404038-B2 Cyclopropyl-bearing liquid crystal compounds and mixtures SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-08-02 US disclosed
US-20160168461-A1 CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-06-16 US disclosed
US-20160168461-A1 CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-06-16 US disclosed