Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693549 | 0.91 | MET (0.54) | METKDRAXLRETKIT | |
| SCHEMBL4401200 | 0.91 | MET (0.54) | METKDRAXLRETKIT | |
| SCHEMBL374458 | 0.81 | MET (0.48) | METKDRAXLRETKIT | |
| SCHEMBL18256911 | 0.81 | KDR (0.52) | METKDRAXLRETKIT | |
| SCHEMBL15279408 | 0.79 | GAA (0.44) | METKDRAXLRETKIT | |
| SCHEMBL18256910 | 0.78 | MET (0.42) | METKDRAXLRETKIT | |
| SCHEMBL21218110 | 0.77 | MET (0.50) | METKDRAXLRETKIT | |
| SCHEMBL4398555 | 0.77 | GAA (0.53) | METKDRAXLRETKIT | |
| SCHEMBL903072 | 0.77 | MET (0.47) | METKDRAXLRETKIT | |
| SCHEMBL12468984 | 0.77 | ALDH1A1 (0.53) | METKDRAXLRETKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299369-A1 | PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-03-28 | — | — | EP | disclosed |