Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 7/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.68 |
| ▸ | ULK1 | O75385 | 1/20 | 0.68 |
| ▸ | CDK7 | P50613 | 1/20 | 0.68 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.68 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.68 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.68 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.68 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.68 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.68 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.68 |
| ▸ | PIM1 | P11309 | 3/20 | 0.66 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.66 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.66 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.66 |
| ▸ | TYK2 | P29597 | 1/20 | 0.66 |
| ▸ | CLK2 | P49760 | 1/20 | 0.66 |
| ▸ | STK32B | Q9NY57 | 1/20 | 0.66 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988139 | 0.84 | CDK5 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1987425 | 0.81 | CDK5 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL19217458 | 0.80 | CDK5 (0.67) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1990603 | 0.80 | PIM1 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1990461 | 0.80 | CDK5 (0.66) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1994872 | 0.78 | CDK5 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1988192 | 0.76 | CDK5 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1995043 | 0.75 | CDK5 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL1990207 | 0.75 | PIM1 (1.00) | CDK5CDK5R1DYRK1AULK1CDK7 | |
| SCHEMBL841808 | 0.74 | CDK5 (0.59) | CDK5CDK5R1DYRK1AULK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152313-A1 | SYNTHESIS OF AGELADINE A AND ANALOGS THEREOF | MACQUARIE UNIVERSITY (AU) | 2011-06-23 | — | — | US | disclosed |
| WO-2009152584-A1 | SYNTHESIS OF AGELADINE A AND ANALOGS THEREOF | MACQUARIE UNIVERSITY (AU) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152313-A1 | SYNTHESIS OF AGELADINE A AND ANALOGS THEREOF | QDPR, ODC1, CROCC | CDK5 710/4885CDK5R1 2029/4885DYRK1A 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.