Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | MYB | P10242 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183713 | 0.78 | ELANE (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL21179481 | 0.70 | ALDH1A1 (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL1097671 | 0.70 | CYP2A6 (0.42) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL3128190 | 0.67 | CYP2A6 (0.36) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL4079696 | 0.65 | CYP2A6 (0.42) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL2008998 | 0.65 | ALDH1A1 (0.42) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL286416 | 0.65 | ALDH1A1 (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL4897405 | 0.65 | ALDH1A1 (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL1605255 | 0.65 | ALDH1A1 (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR | |
| SCHEMBL2012336 | 0.65 | ALDH1A1 (0.39) | TDP1ALDH1A1CYP2A6HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544183-B2 | Uridine nucleoside derivatives, compositions and methods of use | TUFTS UNIVERSITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-20180085386-A1 | URIDINE MONOPHOSPHATE AND TRIPHOSPHATE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | TUFTS UNIVERSITY | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085386-A1 | URIDINE MONOPHOSPHATE AND TRIPHOSPHATE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | P2RY6, UPP1, UMPS | TDP1 99/4885ALDH1A1 3211/4885CYP2A6 1107/4885 |
| US-10544183-B2 | Uridine nucleoside derivatives, compositions and methods of use | P2RY6, UPP1, UMPS | TDP1 97/4885ALDH1A1 2982/4885CYP2A6 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.