Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.45 |
| ▸ | SRPK2 | P78362 | 3/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811110 | 0.77 | ALK (0.58) | ALKSRPK2SRPK1 | |
| SCHEMBL897126 | 0.76 | ALK (0.72) | ALK | |
| SCHEMBL16775670 | 0.75 | ALK (0.66) | ALK | |
| SCHEMBL897087 | 0.73 | ALK (0.61) | ALKSRPK2SRPK1DYRK3CLK1 | |
| SCHEMBL16775671 | 0.73 | ALK (0.78) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL1755787 | 0.70 | ALK (0.55) | ALKSRPK2SRPK1DYRK3CLK1 | |
| SCHEMBL21443134 | 0.69 | CA1 (0.37) | ALK | |
| SCHEMBL21443130 | 0.68 | ALK (0.74) | ALK | |
| SCHEMBL20004681 | 0.66 | ALK (0.72) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897421 | 0.66 | ALK (0.69) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |