Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898287 | 0.91 | MAPT (0.33) | MAPTTSHRL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL898491 | 0.81 | ALK (0.45) | CSNK1G2 | |
| SCHEMBL24676748 | 0.79 | L3MBTL1 (0.37) | L3MBTL1ARCSNK1DCSNK1G2 | |
| SCHEMBL17434476 | 0.78 | TTR (0.35) | MAPTSMN1; SMN2CNR2CYP3A4ALOX15 | |
| SCHEMBL897523 | 0.74 | MAPT (0.36) | MAPTTSHRL3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL17448484 | 0.71 | ALK (0.42) | CSNK1G2 | |
| SCHEMBL10246563 | 0.70 | ALK (0.46) | CSNK1G2 | |
| Iodide SCHEMBL898117 | 0.70 | ALK (0.46) | CSNK1G2 | |
| Iodide SCHEMBL29962380 | 0.70 | ALK (0.46) | CSNK1G2 | |
| SCHEMBL24676630 | 0.70 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |