Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676748 | 0.91 | L3MBTL1 (0.37) | L3MBTL1CSNK1DCSNK1A1GSK3BCSNK1G2 | |
| SCHEMBL898010 | 0.90 | L3MBTL1 (0.36) | L3MBTL1RAB9AKIF11CSNK1DCSNK1A1 | |
| SCHEMBL28351222 | 0.84 | L3MBTL1 (0.36) | L3MBTL1MEN1KMT2AKDM4EALK | |
| SCHEMBL898346 | 0.82 | L3MBTL1 (0.36) | L3MBTL1CSNK1DCSNK1A1GSK3BCSNK1G2 | |
| SCHEMBL31540875 | 0.82 | L3MBTL1 (0.36) | L3MBTL1CSNK1DCSNK1A1GSK3BCSNK1G2 | |
| SCHEMBL23639626 | 0.80 | L3MBTL1 (0.39) | L3MBTL1CSNK1DCSNK1A1GSK3BCSNK1G2 | |
| SCHEMBL19281884 | 0.79 | ALK (0.52) | CSNK1G2ALKEML4 | |
| SCHEMBL28319539 | 0.79 | L3MBTL1 (0.38) | L3MBTL1CSNK1DCSNK1A1GSK3BCSNK1G2 | |
| SCHEMBL897230 | 0.79 | LMNA (0.47) | L3MBTL1KDM4EALKALDH1A1 | |
| SCHEMBL897877 | 0.79 | PDE5A (0.40) | L3MBTL1KDM4EALKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142119-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | L3MBTL1 200/4885RAB9A 2620/4885KIF11 1704/4885 |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | L3MBTL1 200/4885RAB9A 2620/4885KIF11 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.