Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004729 | 0.78 | MAPT (0.45) | MAPTSNCA | |
| SCHEMBL20004585 | 0.76 | MAPT (0.49) | MAPTSNCARIPK1 | |
| SCHEMBL30313250 | 0.69 | MAPT (0.47) | MAPTSNCARIPK1DAO | |
| SCHEMBL20004279 | 0.67 | SNCA (0.68) | MAPTSNCARIPK1DAORET | |
| SCHEMBL342758 | 0.67 | MAPT (0.60) | MAPTSNCARIPK1DAO | |
| SCHEMBL20004547 | 0.65 | MAPT (0.58) | MAPTSNCARIPK1DAORET | |
| SCHEMBL22150197 | 0.64 | MAPT (0.56) | MAPTSNCARIPK1DAO | |
| SCHEMBL3155901 | 0.64 | DAO (0.54) | MAPTSNCARIPK1DAO | |
| SCHEMBL13732919 | 0.64 | MAPT (0.51) | MAPTSNCARIPK1DAO | |
| SCHEMBL22537694 | 0.64 | SNCA (0.55) | MAPTSNCARIPK1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |