Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004729 | 0.78 | MAPT (0.45) | MAPTSNCA | |
| SCHEMBL20004277 | 0.76 | MAPT (0.42) | MAPTSNCARIPK1 | |
| SCHEMBL20005045 | 0.73 | SNCA (0.72) | MAPTSNCARIPK1 | |
| SCHEMBL20005061 | 0.71 | SNCA (0.55) | MAPTSNCAHRH4HRH3DRD2 | |
| SCHEMBL20004553 | 0.66 | SNCA (1.00) | MAPTSNCA | |
| SCHEMBL20004674 | 0.65 | SNCA (0.60) | MAPTSNCADRD2DRD4DRD3 | |
| SCHEMBL22537556 | 0.65 | SNCA (0.53) | MAPTSNCAHRH4HRH3RIPK1 | |
| SCHEMBL20004711 | 0.65 | SNCA (0.80) | MAPTSNCARIPK1 | |
| SCHEMBL20004597 | 0.64 | SNCA (0.94) | MAPTSNCARIPK1 | |
| SCHEMBL20004397 | 0.64 | SNCA (0.73) | MAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |