SCHEMBL20004729

SCHEMBL20004729

CN(CCI)C1=CCC(C#Cc2cc3cccnc3[nH]2)C=C1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
SNCA P37840 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004585 0.78 MAPT (0.49) MAPTSNCA
SCHEMBL20004277 0.78 MAPT (0.42) MAPTSNCA
SCHEMBL22537777 0.73 SNCA (0.79) MAPTSNCA
SCHEMBL22537694 0.66 SNCA (0.55) MAPTSNCA
SCHEMBL30313250 0.65 MAPT (0.47) MAPTSNCA
SCHEMBL342758 0.64 MAPT (0.60) MAPTSNCA
SCHEMBL22150197 0.63 MAPT (0.56) MAPTSNCA
SCHEMBL20004470 0.63 SNCA (0.81) MAPTSNCA
SCHEMBL22930176 0.62 SNCA (0.77) MAPTSNCA
SCHEMBL20005089 0.62 SNCA (0.79) MAPTSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018055316-A1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-03-29 WO disclosed