Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.38 |
| ▸ | CLK3 | P49761 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494057 | 0.83 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL21957317 | 0.77 | DAO (0.65) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL4805509 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL1853725 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL28809999 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL31691908 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL27851181 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL28383003 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL26018015 | 0.73 | PARP1 (0.45) | DAOPDE3BPDE3AMAPT | |
| SCHEMBL5314190 | 0.72 | MAPT (0.51) | DAOPDE3BPDE3AMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107043395-A | A kind of synthetic method of azaindole substituted boracic acid class compound | 江苏常州酞青新材料科技有限公司 | 2017-08-15 | — | — | CN | claimed |
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-02-02 | — | — | US | disclosed |
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-02-02 | — | — | US | disclosed |
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-07-11 | — | — | US | disclosed |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-07-11 | — | — | US | disclosed |
| WO-2018109198-A1 | BICYCLIC OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2018-06-21 | — | — | WO | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |
| CN-105579451-B | Novel 1- (4-pyrimidinyl) -1H-pyrrolo [3,2-c ] pyridine derivatives as NIK inhibitors | 詹森药业有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-107043395-A | A kind of synthetic method of azaindole substituted boracic acid class compound | 江苏常州酞青新材料科技有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105579451-A | Novel 1- (4-pyrimidinyl) -1H-pyrrolo [3,2-c ] pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV | 2016-05-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | PSEN2, CLN6, MAPT | DAO 1775/4885PDE3B 1332/4885PDE3A 1696/4885 |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | PSEN2, SNCA, MAPT | DAO 2202/4885PDE3B 1903/4885PDE3A 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.