Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491546 | 0.83 | DAO (0.53) | DAOAOC3PDE3BPDE3AMAPT | |
| SCHEMBL20004291 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL27851181 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL1853725 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL31691908 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL4805509 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL28809999 | 0.75 | DAO (0.53) | DAOPDE3BPDE3AMAPTSNCA | |
| SCHEMBL6066464 | 0.75 | LOXL2 (0.56) | DAOPDE3BPDE3AMAPTSNCA | |
| Hydrochloric Acid SCHEMBL27144900 | 0.73 | LOXL2 (0.55) | DAOAOC3PDE3BPDE3AMAPT | |
| Hydrochloric Acid SCHEMBL27140516 | 0.73 | LOXL2 (0.55) | DAOAOC3PDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |