Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 5/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537899 | 0.80 | SNCA (0.49) | SNCAMAPTADK | |
| SCHEMBL22537866 | 0.71 | SNCA (0.48) | SNCAMAPTMEN1NPC1RAB9A | |
| SCHEMBL22537667 | 0.71 | SNCA (0.59) | SNCAMAPTADK | |
| SCHEMBL9804473 | 0.68 | CHRM5 (0.62) | SNCAMAPTMEN1NPC1RAB9A | |
| SCHEMBL20004389 | 0.68 | SNCA (1.00) | SNCAMAPT | |
| SCHEMBL22537780 | 0.68 | SNCA (0.49) | SNCAMAPTADK | |
| SCHEMBL10300053 | 0.67 | ALDH1A1 (0.65) | SNCAMAPTTDP1ADK | |
| SCHEMBL770159 | 0.67 | ALDH1A1 (0.65) | SNCAMAPTTDP1ADK | |
| SCHEMBL20004310 | 0.67 | SNCA (1.00) | SNCAMAPTADK | |
| SCHEMBL20004678 | 0.65 | SNCA (0.49) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |