Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537780 | 0.80 | SNCA (0.49) | SNCAMAPTAPP | |
| SCHEMBL22537615 | 0.79 | SNCA (0.56) | SNCAMAPTAPP | |
| SCHEMBL22537823 | 0.71 | SNCA (0.59) | SNCAMAPTAPP | |
| SCHEMBL484098 | 0.70 | SNCA (0.53) | SNCAMAPTAPP | |
| SCHEMBL20005107 | 0.69 | SNCA (0.38) | SNCAMAPT | |
| SCHEMBL9153748 | 0.67 | GRM5 (0.50) | ACACB | |
| SCHEMBL20004677 | 0.66 | SNCA (1.00) | SNCAMAPTAPP | |
| SCHEMBL22537899 | 0.66 | SNCA (0.49) | SNCAMAPTAPP | |
| SCHEMBL20004390 | 0.65 | SNCA (0.51) | SNCAMAPT | |
| SCHEMBL9154247 | 0.64 | GRM5 (0.47) | SNCAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |