Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537774 | 0.93 | APP (0.48) | APP | |
| SCHEMBL22537813 | 0.85 | APP (0.33) | APPSNCAMAPT | |
| SCHEMBL20004453 | 0.81 | SNCA (0.36) | SNCAMAPT | |
| SCHEMBL22537621 | 0.80 | CYP1B1 (0.36) | APPMAPTCYP1B1 | |
| SCHEMBL20005146 | 0.79 | SNCA (0.36) | SNCAMAPT | |
| SCHEMBL22537542 | 0.79 | SNCA (0.39) | SNCAMAPT | |
| SCHEMBL22537754 | 0.77 | SNCA (0.52) | APPSNCAMAPT | |
| SCHEMBL21147267 | 0.77 | SNCA (0.51) | APPSNCAMAPT | |
| SCHEMBL22537807 | 0.73 | ACACB (0.34) | — | |
| SCHEMBL20005013 | 0.73 | GRM5 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |