Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21147267 | 0.86 | SNCA (0.51) | SNCAMAPT | |
| SCHEMBL20004453 | 0.86 | SNCA (0.36) | SNCAMAPTGRM5 | |
| SCHEMBL21147086 | 0.85 | GRM5 (0.41) | SNCAMAPTGRM5FFAR1 | |
| SCHEMBL20004555 | 0.85 | APP (0.39) | SNCAMAPT | |
| SCHEMBL20004515 | 0.79 | APP (0.38) | SNCAMAPT | |
| SCHEMBL20004527 | 0.79 | SNCA (0.37) | SNCAMAPT | |
| SCHEMBL22537542 | 0.79 | SNCA (0.39) | SNCAMAPT | |
| SCHEMBL20005013 | 0.77 | GRM5 (0.40) | GRM5CA12CA1CA2CA9 | |
| SCHEMBL21147289 | 0.77 | PIK3CA (0.38) | FFAR1 | |
| SCHEMBL22537754 | 0.77 | SNCA (0.52) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |