SCHEMBL20004672

SCHEMBL20004672

C/N=N\C(=C/NCCN(C)c1ccc(C#Cc2cc3c([nH]2)=NCC(F)C=3)cc1)CO

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004616 0.80 SNCA (0.41) SNCAMAPT
SCHEMBL20004675 0.78 SNCA (0.43) SNCAMAPT
SCHEMBL22537770 0.77 SNCA (0.56) SNCAMAPT
SCHEMBL20005113 0.77 SNCA (0.39) SNCAMAPT
SCHEMBL20004510 0.74 SNCA (0.47) SNCAMAPT
SCHEMBL20004394 0.69 SNCA (0.42) SNCAMAPT
SCHEMBL22537545 0.68 LTA4H (0.33) SNCAMAPT
SCHEMBL20005042 0.65 SNCA (0.46) SNCAMAPT
SCHEMBL20005071 0.63 MAPT (0.31) SNCAMAPT
SCHEMBL22537718 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018055316-A1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-03-29 WO disclosed