Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004616 | 0.89 | SNCA (0.41) | SNCAMAPT | |
| SCHEMBL20004394 | 0.87 | SNCA (0.42) | SNCAMAPTAPP | |
| SCHEMBL20004675 | 0.85 | SNCA (0.43) | SNCAMAPT | |
| SCHEMBL20004510 | 0.81 | SNCA (0.47) | SNCAMAPTAPP | |
| SCHEMBL20004672 | 0.77 | SNCA (0.35) | SNCAMAPT | |
| SCHEMBL22537545 | 0.74 | LTA4H (0.33) | SNCAMAPT | |
| SCHEMBL21115282 | 0.72 | SNCA (0.66) | SNCAMAPTAPP | |
| SCHEMBL20005071 | 0.71 | MAPT (0.31) | SNCAMAPT | |
| SCHEMBL20005042 | 0.71 | SNCA (0.46) | SNCAMAPTAPP | |
| SCHEMBL22537726 | 0.68 | GABRP (0.34) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |