Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537675 | 0.79 | APP (0.38) | SNCANTRK1CYP2D6HRH3 | |
| SCHEMBL20004399 | 0.71 | SNCA (0.75) | SNCAMAPTNTRK1 | |
| SCHEMBL22537602 | 0.69 | SNCA (0.37) | SNCAMAPTTAAR1 | |
| SCHEMBL20004678 | 0.69 | SNCA (0.49) | SNCAMAPT | |
| SCHEMBL22537604 | 0.64 | MAPT (0.41) | SNCAMAPTHRH3 | |
| SCHEMBL15613386 | 0.63 | HRH3 (0.40) | MAPTTAAR1HRH3 | |
| SCHEMBL20005091 | 0.63 | SNCA (0.58) | SNCAMAPT | |
| SCHEMBL20004669 | 0.62 | SNCA (0.73) | SNCAMAPT | |
| SCHEMBL20004716 | 0.61 | SNCA (0.68) | SNCAMAPT | |
| SCHEMBL20004675 | 0.61 | SNCA (0.43) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |