SCHEMBL20004784

SCHEMBL20004784

CCCCSc1ccc(-c2cc(C)c(C#Cc3ccc(-c4ccc(C)cc4)cc3)cc2F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HTT P42858 2/20 0.35
AR P10275 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC2A1 P11166 1/20 0.33
HPGD P15428 1/20 0.33
XDH P47989 1/20 0.33
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005229 0.88 AR (0.32) ALDH1A1ARNPC1RAB9ASMN1; SMN2
SCHEMBL20005232 0.83 FFAR4 (0.38) ALDH1A1ARMAPTNPC1RAB9A
SCHEMBL19999454 0.81 FFAR1 (0.43) TSHRFFAR1
SCHEMBL20005210 0.80 ACACB (0.42) MAPTMAOBFFAR1
SCHEMBL20006883 0.80 FFAR1 (0.42) TSHRFFAR1
SCHEMBL20005267 0.80 RARA (0.39) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL20004894 0.80 RARA (0.39) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL20004870 0.79 FFAR1 (0.45) CYP1A2FFAR1
SCHEMBL20005228 0.78 FFAR1 (0.43) FFAR1
SCHEMBL20004878 0.78 HRH3 (0.38) TSHRFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed