Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005289 | 0.96 | AKR1C3 (0.33) | GRM5AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL20004910 | 0.94 | GRM5 (0.33) | GRM5AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL19999441 | 0.94 | GRM5 (0.34) | GRM5AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL20004646 | 0.92 | KDM1A (0.31) | PDE3BPDE3AKDM1A | |
| SCHEMBL20005223 | 0.92 | GRM5 (0.34) | GRM5PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL20004915 | 0.91 | PDE3B (0.33) | AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL20005288 | 0.90 | PDE3B (0.32) | AKR1C3AKR1C2PDE3BPDE3AAKR1B10 | |
| SCHEMBL20005248 | 0.89 | GRM5 (0.32) | GRM5PDE3BPDE3A | |
| SCHEMBL20005243 | 0.89 | PDE9A (0.33) | PDE3BPDE3A | |
| SCHEMBL20004824 | 0.88 | KDM1A (0.35) | GRM5AKR1C3AKR1C2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |